| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50198296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453342 (CHEMBL902496) |
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| Ki | 319±n/a nM |
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| Citation |  Grundt, P; Husband, SL; Luedtke, RR; Taylor, M; Newman, AH Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR. Bioorg Med Chem Lett17:745-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50198296 |
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| n/a |
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| Name | BDBM50198296 |
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| Synonyms: | 1-((1H-indol-3-yl)methyl)-4-(4-(methylthio)phenyl)piperidin-4-ol | CHEMBL401031 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2OS |
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| Mol. Mass. | 352.493 |
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| SMILES | CSc1ccc(cc1)C1(O)CCN(Cc2c[nH]c3ccccc23)CC1 |
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| Structure | 
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