| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50282502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2284160 |
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| IC50 | 3000±n/a nM |
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| Citation |  Tripathi, AC; Upadhyay, S; Paliwal, S; Saraf, SK Privileged scaffolds as MAO inhibitors: Retrospect and prospects. Eur J Med Chem145:445-497 (2018) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) |
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| Type: | Enzyme |
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| Mol. Mass.: | 67792.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22303 |
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| Residue: | 614 |
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| Sequence: | MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
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| BDBM50282502 |
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| n/a |
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| Name | BDBM50282502 |
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| Synonyms: | 7-(4-Fluoro-benzyloxy)-3,4-dimethyl-chromen-2-one | 7-(4-fluorobenzyloxy)-3,4-dimethyl-2H-chromen-2-one | CHEMBL276076 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15FO3 |
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| Mol. Mass. | 298.3083 |
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| SMILES | Cc1c(C)c(=O)oc2cc(OCc3ccc(F)cc3)ccc12 |
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| Structure | 
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