| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50007617 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2284567 |
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| Ki | 360±n/a nM |
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| Citation |  Rocha, DA; Silva, EB; Fortes, IS; Lopes, MS; Ferreira, RS; Andrade, SF Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors. Eur J Med Chem157:1426-1459 (2018) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50007617 |
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| n/a |
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| Name | BDBM50007617 |
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| Synonyms: | CHEMBL3233081 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16FN3O2 |
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| Mol. Mass. | 313.3262 |
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| SMILES | Fc1ccccc1OCC(=O)NCCc1nc2ccccc2[nH]1 |
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| Structure | 
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