| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50199303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_412204 (CHEMBL910043) |
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| Ki | 430±n/a nM |
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| Citation |  Vu, CB; Kiesman, WF; Conlon, PR; Lin, KC; Tam, M; Petter, RC; Smits, G; Lutterodt, F; Jin, X; Chen, L; Zhang, J Tricyclic imidazoline derivatives as potent and selective adenosine A1 receptor antagonists. J Med Chem49:7132-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50199303 |
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| n/a |
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| Name | BDBM50199303 |
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| Synonyms: | 8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione | CHEMBL218458 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28N4O3 |
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| Mol. Mass. | 360.4506 |
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| SMILES | CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CCC(O)(CC1)CC2 |
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| Structure | 
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