| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK3 |
|---|
| Ligand | BDBM50567047 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2290895 |
|---|
| IC50 | 2967±n/a nM |
|---|
| Citation |  Lindberg, MF; Deau, E; Arfwedson, J; George, N; George, P; Alfonso, P; Corrionero, A; Meijer, L Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases. J Med Chem66:4106-4130 (2023) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein kinase CLK3 |
|---|
| Name: | Dual specificity protein kinase CLK3 |
|---|
| Synonyms: | CDC2-like kinase 3 (CLK3) | CLK3 | CLK3_HUMAN | Dual specificity protein kinase CLK3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73570.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 638 |
|---|
| Sequence: | MPVLSARRRELADHAGSGRRSGPSPTARSGPHLSALRAQPARAAHLSGRGTYVRRDTAGG
GPGQARPLGPPGTSLLGRGARRSGEGWCPGAFESGARAARPPSRVEPRLATAASREGAGL
PRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEG
RLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHR
RRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWL
QERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKD
KENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALR
FLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHT
TIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGP
IPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRM
LEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
|
|
|
|---|
| BDBM50567047 |
|---|
| n/a |
|---|
| Name | BDBM50567047 |
|---|
| Synonyms: | CHEMBL4848254 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H12N6 |
|---|
| Mol. Mass. | 240.2639 |
|---|
| SMILES | CN(C)c1nccc(n1)-c1cnn2ncccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
