| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Ligand | BDBM50613633 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2292752 |
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| Ki | >100000±n/a nM |
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| Citation |  Dunyak, BM; Gestwicki, JE Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds. J Med Chem59:9622-9644 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Synonyms: | FK506 binding protein 4 | FKBP4 | FKBP4_HUMAN | FKBP52 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51793.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_154482 |
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| Residue: | 459 |
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| Sequence: | MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
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| BDBM50613633 |
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| n/a |
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| Name | BDBM50613633 |
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| Synonyms: | CHEMBL5271713 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H49NO11 |
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| Mol. Mass. | 719.8172 |
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| SMILES | COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)[C@H](CC2CC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| |
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| Structure | 
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