| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 7 |
|---|
| Ligand | BDBM58360 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2296164 |
|---|
| EC50 | 64±n/a nM |
|---|
| Citation |  Dickson, L; Teall, M; Chevalier, E; Cheung, T; Liwicki, GM; Mack, S; Stephenson, A; White, K; Fosbeary, R; Harrison, DC; Brice, NL; Doyle, K; Ciccocioppo, R; Wu, C; Almond, S; Patel, TR; Mitchell, P; Barnes, M; Ayscough, AP; Dawson, LA; Carlton, M; Bürli, RW Discovery of ACS Med Chem Lett14:442-449 (2023) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 7 |
|---|
| Name: | Metabotropic glutamate receptor 7 |
|---|
| Synonyms: | GPRC1G | GRM7 | GRM7 protein | GRM7_HUMAN | MGLUR7 | Metabotropic glutamate receptor 7 | metabotropic glutamate 7 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 102262.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q14831 |
|---|
| Residue: | 915 |
|---|
| Sequence: | MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF
QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP
CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML
GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNS
PAAKKKYVSYNNLVI
|
|
|
|---|
| BDBM58360 |
|---|
| n/a |
|---|
| Name | BDBM58360 |
|---|
| Synonyms: | MLS001173561 | N,N'-bis(diphenylmethyl)ethane-1,2-diamine | N,N'-dibenzhydrylethane-1,2-diamine | SMR000538659 | benzhydryl-[2-(benzhydrylamino)ethyl]amine | cid_1894361 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H28N2 |
|---|
| Mol. Mass. | 392.5353 |
|---|
| SMILES | C(CNC(c1ccccc1)c1ccccc1)NC(c1ccccc1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
