| Reaction Details |
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 | Report a problem with these data |
| Target | Elastase |
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| Ligand | BDBM50614323 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2296493 |
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| Ki | 41±n/a nM |
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| Citation |  Wagner, S; Sommer, R; Hinsberger, S; Lu, C; Hartmann, RW; Empting, M; Titz, A Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections. J Med Chem59:5929-69 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Elastase |
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| Name: | Elastase |
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| Synonyms: | ELAS_PSEAE | Pseudolysin | lasB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53687.94 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_619859 |
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| Residue: | 498 |
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| Sequence: | MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKA
IRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTT
AAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFV
IDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMN
SSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMK
VHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMN
EAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVH
HSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSA
ADVTRAFSTVGVTCPSAL
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| BDBM50614323 |
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| n/a |
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| Name | BDBM50614323 |
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| Synonyms: | CHEMBL4754924 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O4S |
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| Mol. Mass. | 401.479 |
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| SMILES | NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CS |r| |
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| Structure | 
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