| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50085327 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2296943 |
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| IC50 | 840±n/a nM |
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| Citation |  Conroy, S; Kindon, N; Kellam, B; Stocks, MJ Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development. J Med Chem59:9981-10005 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50085327 |
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| n/a |
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| Name | BDBM50085327 |
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| Synonyms: | CHEMBL108166 | MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-methylamino-purin-9-yl)-2-phosphonooxymethyl-butyl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C11H18ClN5O8P2 |
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| Mol. Mass. | 445.69 |
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| SMILES | CNc1nc(Cl)nc2n(CCC(COP(O)(O)=O)COP(O)(O)=O)cnc12 |
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| Structure | 
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