| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50101892 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2296977 |
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| IC50 | 170±n/a nM |
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| Citation |  Conroy, S; Kindon, N; Kellam, B; Stocks, MJ Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development. J Med Chem59:9981-10005 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50101892 |
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| n/a |
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| Name | BDBM50101892 |
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| Synonyms: | 2-(7-Ethoxy-4-hydroxy-2,2-dioxo-2H-2lambda*6*,9-dithia-1,4a-diaza-fluoren-3-yl)-2-oxo-ethanesulfonic acid (6-ethoxy-benzothiazol-2-yl)-amide | CHEMBL540200 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O8S4 |
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| Mol. Mass. | 596.676 |
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| SMILES | CCOc1ccc2N3C(Sc2c1)=NS(=O)(=O)C(C(=O)CS(=O)(=O)Nc1nc2ccc(OCC)cc2s1)C3=O |c:13| |
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| Structure | 
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