| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50479982 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2297002 |
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| Ki | 8.0±n/a nM |
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| Citation |  Hassan, MZ; Osman, H; Ali, MA; Ahsan, MJ Therapeutic potential of coumarins as antiviral agents. Eur J Med Chem123:236-255 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50479982 |
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| n/a |
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| Name | BDBM50479982 |
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| Synonyms: | Aptivus | CHEBI:63628 | Tipranavir | U-140690 | US10806794, Compound Tipranavir |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33F3N2O5S |
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| Mol. Mass. | 602.664 |
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| SMILES | CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1 |t:15| |
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| Structure | 
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