| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM50201172 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_441415 (CHEMBL891644) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Choo, CY; Hirasawa, Y; Karimata, C; Koyama, K; Sekiguchi, M; Kobayashi, J; Morita, H Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase. Bioorg Med Chem15:1703-7 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | ACES_BOVIN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67659.62 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 613 |
|---|
| Sequence: | MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
|
|
|
|---|
| BDBM50201172 |
|---|
| n/a |
|---|
| Name | BDBM50201172 |
|---|
| Synonyms: | (4aS,5S,7S,8aS)-7-methyl-5-(1-oxy-3,4,5,6-tetrahydro-pyridin-2-ylmethyl)-decahydro-quinoline | CHEMBL395790 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H28N2O |
|---|
| Mol. Mass. | 264.4063 |
|---|
| SMILES | C[C@H]1C[C@@H](CC2=[N+]([O-])CCCC2)[C@@H]2CCCN[C@H]2C1 |c:5| |
|---|
| Structure | 
|
|---|
Search and Browse
