| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-3 |
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| Ligand | BDBM50615275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2300990 |
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| IC50 | 10220±n/a nM |
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| Citation |  Crawford, TD; Vartanian, S; Côté, A; Bellon, S; Duplessis, M; Flynn, EM; Hewitt, M; Huang, HR; Kiefer, JR; Murray, J; Nasveschuk, CG; Pardo, E; Romero, FA; Sandy, P; Tang, Y; Taylor, AM; Tsui, V; Wang, J; Wang, S; Zawadzke, L; Albrecht, BK; Magnuson, SR; Cochran, AG; Stokoe, D Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Bioorg Med Chem Lett27:3534-3541 (2017) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-3 |
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| Name: | Stromelysin-3 |
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| Synonyms: | MMP11_MOUSE | Matrix metalloproteinase 11 | Mmp11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55452.62 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_106453 |
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| Residue: | 492 |
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| Sequence: | MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALP
NTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILR
FPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGI
LAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPF
YTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCET
SFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWF
FQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQ
RVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPD
FFDCAEPANTFR
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| BDBM50615275 |
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| n/a |
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| Name | BDBM50615275 |
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| Synonyms: | CHEMBL5282240 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2O3 |
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| Mol. Mass. | 352.4269 |
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| SMILES | COc1cc(ccc1-c1cn(C\C=C\C)c(=O)c2[nH]ccc12)C(C)(C)O |
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| Structure | 
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