| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50203372 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_441841 (CHEMBL890992) |
|---|
| Ki | 155±n/a nM |
|---|
| Citation |  Carato, P; Graulich, A; Jensen, N; Roth, BL; Liégeois, JF Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part II: Influence of the substitution on the benzyl moiety on the affinity for D2L, D4.2, and 5-HT2A receptors. Bioorg Med Chem Lett17:1570-4 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50203372 |
|---|
| n/a |
|---|
| Name | BDBM50203372 |
|---|
| Synonyms: | CHEMBL395632 | naphthalene-1-carboxylic acid [1-(2-methyl-benzyl)-piperidin-4-yl]-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H26N2O |
|---|
| Mol. Mass. | 358.476 |
|---|
| SMILES | Cc1ccccc1CN1CCC(CC1)NC(=O)c1cccc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
