| Reaction Details |
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 | Report a problem with these data |
| Target | Melanin-concentrating hormone receptor 2 |
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| Ligand | BDBM50211164 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_455555 (CHEMBL886334) |
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| Ki | >10000±n/a nM |
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| Citation |  Balavoine, F; Malabre, P; Alleaume, T; Rey, A; Cherfils, V; Jeanneton, O; Seigneurin-Venin, S; Revah, F Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists. Bioorg Med Chem Lett17:3754-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanin-concentrating hormone receptor 2 |
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| Name: | Melanin-concentrating hormone receptor 2 |
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| Synonyms: | GPR145 | MCHR2 | MCHR2_HUMAN | Melanin Concentrating Hormone 2 | Melanin-concentrating hormone receptor | Melanin-concentrating hormone receptor 2 | SLT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38862.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Melanin Concentrating Hormone 2 GPR145 HUMAN::Q969V1 |
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| Residue: | 340 |
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| Sequence: | MNPFHASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTII
RSRKKTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFAC
SAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLWAASFILALPVWVYSKVIKFKDG
VESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPS
VPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSS
INPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF
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| BDBM50211164 |
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| n/a |
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| Name | BDBM50211164 |
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| Synonyms: | (Z)-5-(4-(pyrrolidin-1-ylmethyl)benzylidene)-3-(4-phenoxyphenyl)imidazolidine-2,4-dione | CHEMBL440229 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N3O3 |
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| Mol. Mass. | 439.5057 |
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| SMILES | O=C1N\C(=C/c2ccc(CN3CCCC3)cc2)C(=O)N1c1ccc(Oc2ccccc2)cc1 |
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| Structure | 
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