| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50211684 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436387 (CHEMBL904695) |
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| Ki | >10000±n/a nM |
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| Citation |  Vidal, B; Nueda, A; Esteve, C; Domenech, T; Benito, S; Reinoso, RF; Pont, M; Calbet, M; López, R; Cadavid, MI; Loza, MI; Cárdenas, A; Godessart, N; Beleta, J; Warrellow, G; Ryder, H Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist. J Med Chem50:2732-6 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50211684 |
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| n/a |
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| Name | BDBM50211684 |
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| Synonyms: | 4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipyrimidin-2'-amine | CHEMBL226236 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N7O2 |
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| Mol. Mass. | 347.3308 |
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| SMILES | COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1 |
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| Structure | 
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