| Reaction Details |
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 | Report a problem with these data |
| Target | Malonyl-CoA decarboxylase, mitochondrial |
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| Ligand | BDBM50176179 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_459062 (CHEMBL925154) |
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| IC50 | 170±n/a nM |
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| Citation |  Patel, MR; Talele, TT 3D-QSAR studies on malonyl coenzyme A decarboxylase inhibitors. Bioorg Med Chem15:4470-81 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Malonyl-CoA decarboxylase, mitochondrial |
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| Name: | Malonyl-CoA decarboxylase, mitochondrial |
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| Synonyms: | DCMC_HUMAN | MLYCD | Malonyl-CoA decarboxylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55018.37 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_665404 |
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| Residue: | 493 |
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| Sequence: | MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKT
PAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAA
VLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNG
VLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFF
SHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQG
VELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSEC
KEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVA
NFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQV
LSLVAQFQKNSKL
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| BDBM50176179 |
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| n/a |
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| Name | BDBM50176179 |
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| Synonyms: | 6-((1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-isopropyl-1H-imidazol-5-yl)methoxy)hexanenitrile | CHEMBL202772 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25F6N3O2 |
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| Mol. Mass. | 477.4432 |
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| SMILES | CC(C)c1ncc(COCCCCCC#N)n1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F |
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| Structure | 
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