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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Melanocortin receptor 5 | ||
| Ligand | BDBM50217681 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_448695 (CHEMBL897841) | ||
| Ki | 11000±n/a nM | ||
| Citation |  Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Melanocortin receptor 5 | |||
| Name: | Melanocortin receptor 5 | ||
| Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36612.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P33032 | ||
| Residue: | 325 | ||
| Sequence: |
| ||
| BDBM50217681 | |||
| n/a | |||
| Name | BDBM50217681 | ||
| Synonyms: | CHEMBL238345 | N-(4-hydroxy-2-methoxycinnamyl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)-4-(1H-indol-3-yl)butanamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C35H47N3O3 | ||
| Mol. Mass. | 557.766 | ||
| SMILES | COc1cc(O)ccc1\C=C\CN(C1CCC(CC2CCC(N)CC2)CC1)C(=O)CCCc1c[nH]c2ccccc12 |(13.67,-7.89,;14.99,-7.1,;14.96,-5.56,;13.62,-4.82,;13.59,-3.27,;12.24,-2.52,;14.91,-2.48,;16.26,-3.23,;16.27,-4.77,;17.62,-5.52,;18.94,-4.73,;20.29,-5.49,;21.61,-4.69,;21.58,-3.14,;22.92,-2.35,;22.9,-.8,;21.55,-.03,;21.53,1.51,;22.85,2.29,;24.19,1.52,;25.52,2.3,;25.51,3.85,;26.83,4.62,;24.16,4.6,;22.84,3.82,;20.21,-.83,;20.22,-2.39,;22.96,-5.45,;22.99,-7.01,;24.29,-4.66,;25.63,-5.39,;26.96,-4.62,;28.28,-5.38,;29.7,-4.71,;30.75,-5.84,;30,-7.18,;30.49,-8.63,;29.49,-9.79,;27.97,-9.49,;27.48,-8.04,;28.5,-6.88,)| | ||
| Structure | 
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