| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50221699 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_449695 (CHEMBL898800) |
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| Ki | 13400±n/a nM |
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| Citation |  Drabczynska, A; Müller, CE; Schiedel, A; Schumacher, B; Karolak-Wojciechowska, J; Fruzinski, A; Zobnina, W; Yuzlenko, O; Kiec-Kononowicz, K Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A(1) and A(2A) receptor ligands. Bioorg Med Chem15:6956-74 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50221699 |
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| n/a |
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| Name | BDBM50221699 |
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| Synonyms: | 1,3-dimethyl-9-(2-(pyridin-2-yl)ethyl)-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione | CHEMBL239018 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N6O2 |
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| Mol. Mass. | 340.3797 |
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| SMILES | Cn1c2nc3N(CCc4ccccn4)CCCn3c2c(=O)n(C)c1=O |
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| Structure | 
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