Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 4 | ||
Ligand | BDBM50241836 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_526859 (CHEMBL979354) | ||
Ki | >10000±n/a nM | ||
Citation | Hedner, E; Sjögren, M; Frändberg, PA; Johansson, T; Göransson, U; Dahlström, M; Jonsson, P; Nyberg, F; Bohlin, L Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands. J Nat Prod69:1421-4 (2006) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 4 | |||
Name: | 5-hydroxytryptamine receptor 4 | ||
Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 | ||
Type: | Enzyme | ||
Mol. Mass.: | 43767.54 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q13639 | ||
Residue: | 388 | ||
Sequence: |
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BDBM50241836 | |||
n/a | |||
Name | BDBM50241836 | ||
Synonyms: | CHEMBL511609 | cyclo[(6-bromotryptophan)arginine] | ||
Type | Small organic molecule | ||
Emp. Form. | C17H21BrN6O2 | ||
Mol. Mass. | 421.292 | ||
SMILES | NC(N)=NCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3cc(Br)ccc23)NC1=O |r,wU:7.6,11.11,(32.28,3.26,;30.95,4.04,;30.96,5.58,;29.62,3.28,;28.29,4.05,;26.95,3.29,;25.62,4.07,;24.28,3.3,;22.95,4.08,;21.61,3.31,;20.27,4.08,;21.62,1.78,;20.28,1.01,;20.28,-.53,;21.53,-1.44,;21.05,-2.91,;19.51,-2.9,;18.47,-4.05,;16.96,-3.72,;15.92,-4.86,;16.5,-2.25,;17.53,-1.11,;19.03,-1.44,;22.94,1,;24.27,1.76,;25.6,.98,)| | ||
Structure |