| Reaction Details |
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 | Report a problem with these data |
| Target | IgG receptor FcRn large subunit p51 |
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| Ligand | BDBM50270948 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_552584 (CHEMBL956456) |
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| IC50 | 4600±n/a nM |
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| Citation |  Mezo, AR; McDonnell, KA; Castro, A; Fraley, C Structure-activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction. Bioorg Med Chem16:6394-405 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| IgG receptor FcRn large subunit p51 |
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| Name: | IgG receptor FcRn large subunit p51 |
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| Synonyms: | FCGRN_HUMAN | FCGRT | FCRN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39742.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_627631 |
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| Residue: | 365 |
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| Sequence: | MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
IPATA
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| BDBM50270948 |
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| n/a |
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| Name | BDBM50270948 |
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| Synonyms: | (2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-phenylpropanamido]-3-methyl-3-sulfanylbutanamido]-3-hydroxybutanamido]acetamido}-3-(4-aminophenyl)propanamido]-3-phenylpropanamido]-N-methylacetamido}-N-methylacetamido)-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid | CHEMBL504837 |
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| Type | Small organic molecule |
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| Emp. Form. | C73H103N17O16S2 |
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| Mol. Mass. | 1538.833 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#7])cc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])C([#6])([#6])[#16])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](-[#8])=O |r| |
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| Structure | 
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