| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50251445 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_488064 (CHEMBL983874) |
|---|
| Ki | 3340±n/a nM |
|---|
| Citation |  Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines. Bioorg Med Chem Lett18:3971-3 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50251445 |
|---|
| n/a |
|---|
| Name | BDBM50251445 |
|---|
| Synonyms: | (R)-11-(2-Hydroxy-ethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol | CHEMBL480526 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21NO3 |
|---|
| Mol. Mass. | 311.3749 |
|---|
| SMILES | CN1CCc2cc(O)cc-3c2[C@H]1Cc1cccc(OCCO)c-31 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
