| Reaction Details |
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 | Report a problem with these data |
| Target | Group IIE secretory phospholipase A2 |
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| Ligand | BDBM50053137 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_489275 (CHEMBL990831) |
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| IC50 | 35±n/a nM |
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| Citation |  Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem51:4708-14 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group IIE secretory phospholipase A2 |
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| Name: | Group IIE secretory phospholipase A2 |
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| Synonyms: | PA2GE_MOUSE | Pla2g2e |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15949.46 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_489275 |
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| Residue: | 142 |
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| Sequence: | MKPPIALACLCLLVPLAGGNLVQFGVMIERMTGKPALQYNDYGCYCGVGGSHWPVDETDW
CCHAHDCCYGRLEKLGCDPKLEKYLFSITRDNIFCAGRTACQRHTCECDKRAALCFRHNL
NTYNRKYAHYPNKLCTGPTPPC
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| BDBM50053137 |
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| n/a |
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| Name | BDBM50053137 |
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| Synonyms: | (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indolizin-8-yloxy)-acetic acid | CHEMBL332993 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24N2O5 |
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| Mol. Mass. | 456.4899 |
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| SMILES | CCc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O |
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| Structure | 
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