| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Group IIE secretory phospholipase A2 |
|---|
| Ligand | BDBM50263000 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_489274 (CHEMBL990830) |
|---|
| IC50 | 16±n/a nM |
|---|
| Citation |  Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem51:4708-14 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Group IIE secretory phospholipase A2 |
|---|
| Name: | Group IIE secretory phospholipase A2 |
|---|
| Synonyms: | GIIE sPLA2 | PA2GE_HUMAN | PLA2G2E | Phosphatidylcholine 2-acylhydrolase GIIE | sPLA(2)-IIE |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 15997.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_489274 |
|---|
| Residue: | 142 |
|---|
| Sequence: | MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW
CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL
GTYNRKYAHYPNKLCTGPTPPC
|
|
|
|---|
| BDBM50263000 |
|---|
| n/a |
|---|
| Name | BDBM50263000 |
|---|
| Synonyms: | 2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(phenylsulfonyl)acetamide | CHEMBL446349 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H27N3O6S |
|---|
| Mol. Mass. | 569.628 |
|---|
| SMILES | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
