| Reaction Details |
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 | Report a problem with these data |
| Target | Group IIE secretory phospholipase A2 |
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| Ligand | BDBM50263003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_489274 (CHEMBL990830) |
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| IC50 | 20±n/a nM |
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| Citation |  Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem51:4708-14 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group IIE secretory phospholipase A2 |
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| Name: | Group IIE secretory phospholipase A2 |
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| Synonyms: | GIIE sPLA2 | PA2GE_HUMAN | PLA2G2E | Phosphatidylcholine 2-acylhydrolase GIIE | sPLA(2)-IIE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15997.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_489274 |
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| Residue: | 142 |
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| Sequence: | MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW
CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL
GTYNRKYAHYPNKLCTGPTPPC
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| BDBM50263003 |
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| n/a |
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| Name | BDBM50263003 |
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| Synonyms: | 2-(2-ethyl-3-(o-phenylbenzyl)-8-(2-oxopropoxy)indolizin-1-yl)-2-oxoacetamide | CHEMBL514841 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O3 |
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| Mol. Mass. | 386.4431 |
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| SMILES | CCc1c(C(=O)C(N)=O)c2c(OC)cc3ccccc3c2n1Cc1ccccc1 |
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| Structure | 
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