Reaction Details |
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Target | Melatonin receptor type 1A |
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Ligand | BDBM50263601 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_535635 (CHEMBL987963) |
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Ki | 124±n/a nM |
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Citation | Poissonnier-Durieux, S; Ettaoussi, M; Pérès, B; Boutin, JA; Audinot, V; Bennejean, C; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Lesieur, D; Yous, S Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands. Bioorg Med Chem16:8339-48 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Melatonin receptor type 1A |
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Name: | Melatonin receptor type 1A |
Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
Type: | Enzyme |
Mol. Mass.: | 39392.94 |
Organism: | Homo sapiens (Human) |
Description: | P48039 |
Residue: | 350 |
Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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BDBM50263601 |
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n/a |
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Name | BDBM50263601 |
Synonyms: | CHEMBL478218 | N-[2-(3-(3-Ethoxycarbonylaminophenyl)-7-methoxynaphth-1-yl)ethyl]acetamide |
Type | Small organic molecule |
Emp. Form. | C24H26N2O4 |
Mol. Mass. | 406.4742 |
SMILES | CCOC(=O)Nc1cccc(c1)-c1cc(CCNC(C)=O)c2cc(OC)ccc2c1 |
Structure |
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