Reaction Details |
| Report a problem with these data |
Target | Melatonin receptor type 1B |
---|
Ligand | BDBM50263603 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_535636 (CHEMBL987964) |
---|
Ki | 1.86±n/a nM |
---|
Citation | Poissonnier-Durieux, S; Ettaoussi, M; Pérès, B; Boutin, JA; Audinot, V; Bennejean, C; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Lesieur, D; Yous, S Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands. Bioorg Med Chem16:8339-48 (2008) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Melatonin receptor type 1B |
---|
Name: | Melatonin receptor type 1B |
Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
Type: | Enzyme |
Mol. Mass.: | 40203.54 |
Organism: | Homo sapiens (Human) |
Description: | P49286 |
Residue: | 362 |
Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
BDBM50263603 |
---|
n/a |
---|
Name | BDBM50263603 |
Synonyms: | CHEMBL517502 | N-[2-(3-(2-Hydroxymethylphenyl)-7-methoxynaphth-1-yl)ethyl]acetamide |
Type | Small organic molecule |
Emp. Form. | C22H23NO3 |
Mol. Mass. | 349.4229 |
SMILES | COc1ccc2cc(cc(CCNC(C)=O)c2c1)-c1ccccc1CO |
Structure |
|