| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Disintegrin and metalloproteinase domain-containing protein 33 |
|---|
| Ligand | BDBM26526 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_492649 (CHEMBL953078) |
|---|
| Ki | 15±n/a nM |
|---|
| Citation |  Georgiadis, D; Yiotakis, A Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem16:8781-94 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Disintegrin and metalloproteinase domain-containing protein 33 |
|---|
| Name: | Disintegrin and metalloproteinase domain-containing protein 33 |
|---|
| Synonyms: | ADA33_HUMAN | ADAM33 | C20orf153 | Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 87748.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_492649 |
|---|
| Residue: | 813 |
|---|
| Sequence: | MGWRPRRARGTPLLLLLLLLLLWPVPGAGVLQGHIPGQPVTPHWVLDGQPWRTVSLEEPV
SKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNHTDHCHYQGRV
RGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQLLTWKGTCG
HRDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEV
ANYVDQLLRTLDIQVALTGLEVWTERDRSRVTQDANATLWAFLQWRRGLWAQRPHDSAQL
LTGRAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDPDGC
CVEAAAESGGCVMAAATGHPFPRVFSACSRRQLRAFFRKGGGACLSNAPDPGLPVPPALC
GNGFVEAGEECDCGPGQECRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPAGALCRQAMG
DCDLPEFCTGTSSHCPPDVYLLDGSPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAPEA
CFQVVNSAGDAHGNCGQDSEGHFLPCAGRDALCGKLQCQGGKPSLLAPHMVPVDSTVHLD
GQEVTCRGALALPSAQLDLLGLGLVEPGTQCGPRMVCQSRRCRKNAFQELQRCLTACHSH
GVCNSNHNCHCAPGWAPPFCDKPGFGGSMDSGPVQAENHDTFLLAMLLSVLLPLLPGAGL
AWCCYRLPGAHLQRCSWGCRRDPACSGPKDGPHRDHPLGGVHPMELGPTATGQPWPLDPE
NSHEPSSHPEKPLPAVSPDPQADQVQMPRSCLW
|
|
|
|---|
| BDBM26526 |
|---|
| n/a |
|---|
| Name | BDBM26526 |
|---|
| Synonyms: | (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide | BMCL181958 Compound 1 | CHEMBL148169 | IK682 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27N3O4 |
|---|
| Mol. Mass. | 433.4996 |
|---|
| SMILES | C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO |r| |
|---|
| Structure | 
|
|---|
Search and Browse
