| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-2 |
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| Ligand | BDBM26575 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_497443 (CHEMBL1005437) |
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| Ki | >5346±n/a nM |
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| Citation |  Georgiadis, D; Yiotakis, A Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem16:8781-94 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-2 |
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| Name: | Stromelysin-2 |
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| Synonyms: | MMP10 | MMP10_HUMAN | Matrix Metalloproteinase-10 (MMP-10) | Matrix metalloproteinase 10 | STMY2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 54143.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09238 |
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| Residue: | 476 |
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| Sequence: | MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIV
KKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNY
TPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSL
AHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYN
SFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAIST
LRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFW
AIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQG
FPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
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| BDBM26575 |
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| n/a |
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| Name | BDBM26575 |
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| Synonyms: | (3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]methyl}benzene)oxane-3,4-dicarboxamide | pyrazolopyridine, 49 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21F3N4O4 |
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| Mol. Mass. | 462.4217 |
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| SMILES | ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2c(nn3ccccc23)C(F)(F)F)cc1 |r| |
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| Structure | 
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