| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-hydroxybutyrate receptor |
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| Ligand | BDBM50246038 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_558100 (CHEMBL956590) |
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| IC50 | 400±n/a nM |
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| Citation |  Molnár, T; Visy, J; Simon, A; Moldvai, I; Temesvári-Major, E; Dörnyei, G; Fekete, EK; Kardos, J Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes. Bioorg Med Chem Lett18:6290-2 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-hydroxybutyrate receptor |
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| Name: | Gamma-hydroxybutyrate receptor |
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| Synonyms: | Gamma hydroxybutyric, GHB | Gamma-hydroxybutyrate receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56171.11 |
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| Organism: | RAT |
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| Description: | Gamma hydroxybutyric, GHB 0 RAT::Q6RY99 |
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| Residue: | 512 |
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| Sequence: | MRAAAAGLGPGRLHAWAARRGLGRFPARVPRAAGGRSPCPASISNSRTLRLAAAGNTFCL
ASTLSSGCWEPCSWPSASGPGVRRAFFPTSQGGQIQGGLDPVWLFVVIGGIMSVLGFAGC
IGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDL
QNLIDFAQEYWSCCGARGPNDWNLNIRTSTALTSNPSRERCGVPFFCWVRTLRKTSQYPC
GYTSAQTELEHKIHLHQSWWPFEKWLKKPDGWPGLGAIASFKMGIAGPNPRSTSRQERPT
GKLPGVMATCLAHRAVVGASKDALPHSQWQGLWDVCYDLSPRLCEHGTQEATEAGLGLNW
GCTGAGLGLFTTELCVWGVHMCVCVCVCVCVRVCLCLCVRVRGMHVCALVSTPGVSTPLL
VRWWPFQSFKGDGARRVGHVPASPSLLWDVSLCGLGACCLRPLHIHHDLEPAWSSPWPQC
HSLEMGPRILSVSLSRLPLRTHTWQDGYERLN
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| BDBM50246038 |
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| n/a |
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| Name | BDBM50246038 |
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| Synonyms: | (R)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-ylidene)acetic acid | CHEMBL514926 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14O3 |
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| Mol. Mass. | 218.2485 |
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| SMILES | O[C@H]1c2ccccc2CCC\C1=C/C(O)=O |r| |
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| Structure | 
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