| Reaction Details |
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 | Report a problem with these data |
| Target | Bone morphogenetic protein 1 |
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| Ligand | BDBM50256306 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_518962 (CHEMBL941550) |
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| IC50 | 25±n/a nM |
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| Citation |  Bailey, S; Fish, PV; Billotte, S; Bordner, J; Greiling, D; James, K; McElroy, A; Mills, JE; Reed, C; Webster, R Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg Med Chem Lett18:6562-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bone morphogenetic protein 1 |
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| Name: | Bone morphogenetic protein 1 |
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| Synonyms: | BMP-1 | BMP1 | BMP1_HUMAN | Mammalian tolloid protein | PCOLC | PCP | Procollagen C-proteinase | mTld |
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| Type: | PROTEIN |
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| Mol. Mass.: | 111254.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_518962 |
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| Residue: | 986 |
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| Sequence: | MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN
TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST
PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR
FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY
GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS
DDTITKKGFHLRYTSTKFQDTLHSRK
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| BDBM50256306 |
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| n/a |
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| Name | BDBM50256306 |
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| Synonyms: | (R)-6-cyclohexyl-N-hydroxy-3-(3-(morpholine-4-carbonyl)-1,2,4-oxadiazol-5-yl)hexanamide | CHEMBL525215 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N4O5 |
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| Mol. Mass. | 394.4653 |
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| SMILES | ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)C(=O)N1CCOCC1 |r| |
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| Structure | 
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