| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bone morphogenetic protein 1 |
|---|
| Ligand | BDBM50256205 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_518962 (CHEMBL941550) |
|---|
| IC50 | 57±n/a nM |
|---|
| Citation |  Bailey, S; Fish, PV; Billotte, S; Bordner, J; Greiling, D; James, K; McElroy, A; Mills, JE; Reed, C; Webster, R Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg Med Chem Lett18:6562-7 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bone morphogenetic protein 1 |
|---|
| Name: | Bone morphogenetic protein 1 |
|---|
| Synonyms: | BMP-1 | BMP1 | BMP1_HUMAN | Mammalian tolloid protein | PCOLC | PCP | Procollagen C-proteinase | mTld |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 111254.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_518962 |
|---|
| Residue: | 986 |
|---|
| Sequence: | MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN
TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST
PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR
FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY
GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS
DDTITKKGFHLRYTSTKFQDTLHSRK
|
|
|
|---|
| BDBM50256205 |
|---|
| n/a |
|---|
| Name | BDBM50256205 |
|---|
| Synonyms: | (R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide | CHEMBL480758 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H30N4O4 |
|---|
| Mol. Mass. | 414.498 |
|---|
| SMILES | ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)C(=O)NCc1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
