Ki Summary

Reaction Details

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Target

Solute carrier family 28 member 3

Ligand

BDBM50256076

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_518727 (CHEMBL957102)

53860±n/a nM

Citation

Gupte, A; Buolamwini, JK Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors. Bioorg Med Chem Lett19:917-21 (2009) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Solute carrier family 28 member 3

Name:

Solute carrier family 28 member 3

Synonyms:

CNT3 | S28A3_HUMAN | SLC28A3

Type:

PROTEIN

Mol. Mass.:

76938.51

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1494517

Residue:

691

Sequence:

MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVE
QDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISA
CVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSS
LVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLG
LLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMS
MLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSEL
HAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKN
AMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQL
SFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKF
VNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTV
ACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVI
PGGNHSLYSLKGCCTLLNPSTFNCNGISNTF

BDBM50256076

n/a

Name

BDBM50256076

Synonyms:

1-(2-hydroxy-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone | CHEMBL482065

Type

Small organic molecule

Emp. Form.

C14H18O8

Mol. Mass.

314.2879

SMILES

CC(=O)c1c(O)cccc1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|

Structure