| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NH(3)-dependent NAD(+) synthetase |
|---|
| Ligand | BDBM50266736 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_564355 (CHEMBL957657) |
|---|
| IC50 | 61800±n/a nM |
|---|
| Citation |  Moro, WB; Yang, Z; Kane, TA; Brouillette, CG; Brouillette, WJ Virtual screening to identify lead inhibitors for bacterial NAD synthetase (NADs). Bioorg Med Chem Lett19:2001-5 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NH(3)-dependent NAD(+) synthetase |
|---|
| Name: | NH(3)-dependent NAD(+) synthetase |
|---|
| Synonyms: | BAS1855 | BA_1998 | GBAA_1998 | NADE_BACAN | Nicotinamide adenine dinucleotide synthetase (NADs) | nadE |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 30092.16 |
|---|
| Organism: | Bacillus anthracis |
|---|
| Description: | Q81RP3 |
|---|
| Residue: | 272 |
|---|
| Sequence: | MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQ
LAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYE
NLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLL
PLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKT
VPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
|
|
|
|---|
| BDBM50266736 |
|---|
| n/a |
|---|
| Name | BDBM50266736 |
|---|
| Synonyms: | CHEMBL476429 | N-(2-(5-bromo-2-chlorophenyl)benzo[d]oxazol-5-yl)-3-nitrobenzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H11BrClN3O4 |
|---|
| Mol. Mass. | 472.676 |
|---|
| SMILES | [O-][N+](=O)c1cccc(c1)C(=O)Nc1ccc2oc(nc2c1)-c1cc(Br)ccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
