| Reaction Details |
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 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
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| Ligand | BDBM50278246 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_564380 (CHEMBL962375) |
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| IC50 | 61000±n/a nM |
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| Citation |  Geyer, JA; Keenan, SM; Woodard, CL; Thompson, PA; Gerena, L; Nichols, DA; Gutteridge, CE; Waters, NC Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones. Bioorg Med Chem Lett19:1982-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MO15-related protein kinase Pfmrk |
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| Name: | MO15-related protein kinase Pfmrk |
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| Synonyms: | Protein kinase Pfmrk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37992.30 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_640752 |
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| Residue: | 324 |
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| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
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| BDBM50278246 |
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| n/a |
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| Name | BDBM50278246 |
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| Synonyms: | CHEMBL471667 | ethyl 2-(3-nitrobenzoyl)-3-(pyridin-2-yl)acrylate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O5 |
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| Mol. Mass. | 326.3035 |
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| SMILES | CCOC(=O)C(=C/c1ccccn1)\C(=O)c1cccc(c1)[N+]([O-])=O |
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| Structure | 
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