| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Choline O-acetyltransferase |
|---|
| Ligand | BDBM50280246 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_49106 (CHEMBL665957) |
|---|
| IC50 | 29000±n/a nM |
|---|
| Citation |  Alcalde, E; Roca, T; Barat, A; Ramirez, G; Goya, P; Martinez, A (E)-1-alkyl-[2-(1H-azol-2-yl)vinyl]pyridinium salts: theoretical analysis, synthesis and evaluation of their interaction with choline acetyltransferase. Bioorg Med Chem Lett2:1493-1496 (1992) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Choline O-acetyltransferase |
|---|
| Name: | Choline O-acetyltransferase |
|---|
| Synonyms: | CHAT | CLAT_CHICK | Choline acetylase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 72625.66 |
|---|
| Organism: | Gallus gallus |
|---|
| Description: | ChEMBL_49105 |
|---|
| Residue: | 640 |
|---|
| Sequence: | MPDLEKDMQKKEKDSRSKDEPAVPKLPVPPLQQTLQMYLQCMKHLVPEEQFRKTKSIVEQ
FGVAGGLGESLQLILEERREETTNWVFNYWLDDMYLNNRLALPVNSSPAIIFARQNFKDV
NDQLRFAANLISGVQDYKALLDSHALPVDFARGQLSGQPLCMKQYYGLFSSYRLPGHTKD
TLVAQKSCVMPEPEHIIVACNNQLFVLDVGINFRRLSEGDLFTQLRKIAKMAENEEEMLP
PIGLLTTDGRTEWAEARTILMKDSTNRDSLDMIERCICLVCLDGTSGVELNDTNMALQLL
HGGGYHKNGANRWYDKPMQFVVGRDGVCGTVCEHSPFDGIVLVQCTEHLLKHMKESSKKL
LRADSVSELPAPRRLRWKCSPEIQAHLASSAEKLQRIVKNLDFIAYKFVNYGKEFIKKQK
TSPDAYIQVALQLAFYRCHRRLVPTYESASIRRFDEGRVDNIRSATAEAFAFVKAMIDDK
PALSDSEKMQRFKDAIAAQTNYTILAITGMAIDNHLLGLREVAREHFKELPEIFTDETYL
TSNRFILSTSQVPTPMEMFCCYGPVVPNGYGACYNPQPEHILFCISSFKDCKETSSDMLA
KAVEESLLEIRDLCNKCSSSTAKSLAKQEEATQLRSDRKL
|
|
|
|---|
| BDBM50280246 |
|---|
| n/a |
|---|
| Name | BDBM50280246 |
|---|
| Synonyms: | 4-((E)-2-Naphthalen-1-yl-vinyl)-1-propyl-pyridinium; bromide | 4-(2-Naphthalen-1-yl-vinyl)-1-propyl-pyridinium; bromide | CHEMBL19537 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H20N |
|---|
| Mol. Mass. | 274.379 |
|---|
| SMILES | CCC[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
