| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50280412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_71530 (CHEMBL679996) |
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| IC50 | 1500±n/a nM |
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| Citation |  Valentine, JJ; Nakanishi, S; Hageman, DL; Snider, R; Spencer, RW; Vinick, FJ CP-70,030 and CP-75,998: The first non-peptide antagonists of bombesin and gastrin releasing peptide Bioorg Med Chem Lett2:333-338 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | GRP-R | GRP-preferring bombesin receptor | GRPR_RAT | Gastrin-releasing peptide receptor | Grpr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43254.57 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_12641 |
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| Residue: | 384 |
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| Sequence: | MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMT
SFKSTNPSATFSLINGNICHEGYV
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| BDBM50280412 |
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| n/a |
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| Name | BDBM50280412 |
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| Synonyms: | 2-{3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(E)-ylidene]-1-ethyl-2-oxo-2,3-dihydro-1H-indol-5-yloxymethyl}-benzoic acid | CHEMBL323166 | CP-70030 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H37NO5 |
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| Mol. Mass. | 527.6506 |
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| SMILES | CCN1C(=O)\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)c2cc(OCc3ccccc3C(O)=O)ccc12 |
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| Structure | 
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