| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inositol monophosphatase 1 |
|---|
| Ligand | BDBM50281362 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_140830 |
|---|
| IC50 | 500±n/a nM |
|---|
| Citation |  Fletcher, SR; Baker, R; Ladduwahetty, T; Sharpe, A; Teall, M; Atack, JR 4-hydroxyphenoxymethylene bisphosphonic acid derivatives: potent, non-hydrolysable inhibitors of MYO-inositol monophosphatase Bioorg Med Chem Lett3:141-146 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inositol monophosphatase 1 |
|---|
| Name: | Inositol monophosphatase 1 |
|---|
| Synonyms: | IMPA | IMPA1 | IMPA1_BOVIN | Inositol-1(or 4)-monophosphatase 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30047.72 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_140831 |
|---|
| Residue: | 277 |
|---|
| Sequence: | MADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKE
KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFG
IVYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIE
RLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTG
GPFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDED
|
|
|
|---|
| BDBM50281362 |
|---|
| n/a |
|---|
| Name | BDBM50281362 |
|---|
| Synonyms: | CHEMBL416583 | [1-(4-Hydroxy-phenoxy)-2-phenyl-1-phosphono-ethyl]-phosphonic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H16O8P2 |
|---|
| Mol. Mass. | 374.2196 |
|---|
| SMILES | Oc1ccc(OC(Cc2ccccc2)(P(O)(O)=O)P(O)(O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
