| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50283198 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35129 |
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| IC50 | 0.300000±n/a nM |
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| Citation |  Santella, JB; Duncia, JV; Ensinger, CL; VanAtten, MK; Carini, DJ; Wexler, RR; Chiu, AT; Wong, PC; Timmermans, PB Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position. Bioorg Med Chem Lett4:2235-2240 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM50283198 |
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| n/a |
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| Name | BDBM50283198 |
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| Synonyms: | Biphenylsulfonylcarbamate compound | CHEMBL311018 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H40FN3O7S |
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| Mol. Mass. | 725.825 |
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| SMILES | CCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OCc2cccc(c2)C(=O)c2ccccc2)c(F)c1 |
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| Structure | 
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