| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50285162 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_36623 |
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| IC50 | 520±n/a nM |
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| Citation |  Dorsch, D; Mederski, WW; Osswald, M; Beier, N; Schelling, P Uracil-based angiotensin II receptor antagonists Bioorg Med Chem Lett5:2071-2076 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41107.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_36779 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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| BDBM50285162 |
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| n/a |
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| Name | BDBM50285162 |
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| Synonyms: | 5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | CHEMBL293001 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H26N8O |
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| Mol. Mass. | 502.5697 |
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| SMILES | CCCCc1cc(=O)n2nc(nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1 |
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| Structure | 
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