| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50289068 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_160737 |
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| pH | 4.7±n/a |
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| IC50 | 676±n/a nM |
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| Comments | extracted |
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| Citation |  Hamilton, HW; Tait, BD; Gajda, C; Hagen, SE; Ferguson, D; Lunney, EA; Pavlovsky, A; Tummino, PJ 6-Phenyl-6-alkylamido-5,6-dihydro-2H-pyran-2-ones: novel HIV protease inhibitors Bioorg Med Chem Lett6:719-724 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50289068 |
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| n/a |
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| Name | BDBM50289068 |
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| Synonyms: | CHEMBL159290 | N-Benzyl-4-[4-hydroxy-5-(2-isopropyl-phenylsulfanyl)-6-oxo-2-phenyl-3,6-dihydro-2H-pyran-2-yl]-N-methyl-butyramide |
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| Type | Small organic molecule |
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| Emp. Form. | C32H35NO4S |
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| Mol. Mass. | 529.69 |
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| SMILES | CC(C)c1ccccc1SC1C(=O)CC(CCCC(=O)N(C)Cc2ccccc2)(OC1=O)c1ccccc1 |
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| Structure | 
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