| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50289447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58931 |
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| Ki | 26±n/a nM |
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| Citation |  Wright, JL; Gregory, TF; Heffner, TG; MacKenzie, RG; Pugsley, TA; Meulen, SV; Wise, LD Discovery of selective dopamine D4 receptor antagonists: 1-Aryloxy-3-(4-aryloxypiperidinyl)-2-propanols Bioorg Med Chem Lett7:1377-1380 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50289447 |
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| n/a |
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| Name | BDBM50289447 |
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| Synonyms: | 1-(4-Benzyl-piperidin-1-yl)-3-(naphthalen-1-yloxy)-propan-2-ol | CHEMBL418758 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29NO2 |
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| Mol. Mass. | 375.5033 |
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| SMILES | OC(COc1cccc2ccccc12)CN1CCC(Cc2ccccc2)CC1 |
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| Structure | 
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