| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
|---|
| Ligand | BDBM50290508 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1461 |
|---|
| Ki | 700±n/a nM |
|---|
| Citation |  Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D 5-HT1A and 5-HT2A ligands with anxiolytic and antipanic-like properties Bioorg Med Chem Lett7:2579-2584 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1A |
|---|
| Name: | 5-hydroxytryptamine receptor 1A |
|---|
| Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 46445.29 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Binding assays were performed using rat hippocampal membranes. |
|---|
| Residue: | 422 |
|---|
| Sequence: | MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT
SLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGN
SKEHLPLPSESGSNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RR
|
|
|
|---|
| BDBM50290508 |
|---|
| n/a |
|---|
| Name | BDBM50290508 |
|---|
| Synonyms: | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-(4-morpholin-4-yl-butyl)-3H-benzothiazol-2-one | CHEMBL433345 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H36FN3O3S |
|---|
| Mol. Mass. | 525.678 |
|---|
| SMILES | Fc1ccc(cc1)C(=O)C1CCN(CCn2c3ccc(CCCCN4CCOCC4)cc3sc2=O)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
