| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src |
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| Ligand | BDBM50291651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_202782 |
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| IC50 | 3200±n/a nM |
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| Citation |  Shahripour, A; Para, KS; Plummer, MS; Lunney, EA; Holland, DR; Rubin, JR; Humblet, C; Fergus, JH; Marks, JS; Saltiel, AR; Sawyer, TK Structure-based design of novel, dipeptide ligands targeting the pp60Src SH2 domain Bioorg Med Chem Lett7:1107-1112 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proto-oncogene tyrosine-protein kinase Src |
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| Name: | Proto-oncogene tyrosine-protein kinase Src |
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| Synonyms: | Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src |
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| Type: | Protein |
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| Mol. Mass.: | 59838.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P12931 |
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| Residue: | 536 |
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| Sequence: | MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
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| BDBM50291651 |
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| n/a |
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| Name | BDBM50291651 |
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| Synonyms: | 4-[2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-[2-(4a,5,6,7,8,8a-hexahydro-naphthalen-1-yl)-ethylcarbamoyl]-butyric acid | CHEMBL268031 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H38N3O9P |
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| Mol. Mass. | 591.5898 |
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| SMILES | CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCC1=CC=CC2CCCCC12 |c:34,t:32| |
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| Structure | 
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