| Reaction Details |
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 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
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| Ligand | BDBM50292902 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_494628 (CHEMBL945287) |
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| Kd | 3±n/a nM |
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| Citation |  Tu, Z; Efange, SM; Xu, J; Li, S; Jones, LA; Parsons, SM; Mach, RH Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. J Med Chem52:1358-69 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vesicular acetylcholine transporter |
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| Name: | Vesicular acetylcholine transporter |
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| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56900.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507628 |
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| Residue: | 532 |
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| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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| BDBM50292902 |
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| n/a |
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| Name | BDBM50292902 |
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| Synonyms: | (2R,3R)-3-(4-(aminomethyl)-4-phenylpiperidin-1-yl)-5-iodo-1,2,3,4-tetrahydronaphthalen-2-ol | CHEMBL461783 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27IN2O |
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| Mol. Mass. | 462.3671 |
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| SMILES | NCC1(CCN(CC1)[C@@H]1Cc2c(I)cccc2C[C@H]1O)c1ccccc1 |r| |
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| Structure | 
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