| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine kinase 2 |
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| Ligand | BDBM50293711 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571686 (CHEMBL1032134) |
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| IC50 | 29200±n/a nM |
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| Citation |  Qu, W; Ploessl, K; Truong, H; Kung, MP; Kung, HF Iodophenyl tagged sphingosine derivatives: synthesis and preliminary biological evaluation. Bioorg Med Chem Lett19:3382-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine kinase 2 |
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| Name: | Sphingosine kinase 2 |
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| Synonyms: | SK 2 | SK2 | SPHK2 | SPHK2_HUMAN | SPK 2 | Sphingosine kinase 2 | Sphingosine kinase types 2 (SphK2) |
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| Type: | Protein |
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| Mol. Mass.: | 69221.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NRA0 |
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| Residue: | 654 |
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| Sequence: | MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA
RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY
PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP
PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG
IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL
LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL
GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV
SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA
ALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL
MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL
GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP
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| BDBM50293711 |
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| n/a |
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| Name | BDBM50293711 |
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| Synonyms: | (2S,3R,E)-2-Amino-18-(4-iodophenyl)octadec-4-ene-1,3-diol | CHEMBL559072 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H40INO2 |
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| Mol. Mass. | 501.4844 |
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| SMILES | N[C@@H](CO)[C@H](O)\C=C\CCCCCCCCCCCCCc1ccc(I)cc1 |r| |
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| Structure | 
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