Ki Summary

Reaction Details

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Target

Glucose-6-phosphatase catalytic subunit 1

Ligand

BDBM50294478

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_575563 (CHEMBL1036406)

IC50

87000±n/a nM

Citation

Bisht, SS; Fatima, S; Tamrakar, AK; Rahuja, N; Jaiswal, N; Srivastava, AK; Tripathi, RP Synthetic studies in butenonyl C-glycosides: Preparation of polyfunctional alkanonyl glycosides and their enzyme inhibitory activity. Bioorg Med Chem Lett19:2699-703 (2009) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Glucose-6-phosphatase catalytic subunit 1

Name:

Glucose-6-phosphatase catalytic subunit 1

Synonyms:

G-6-Pase | G6PC1_RAT | G6Pase | G6pc | G6pc1 | G6pt | Glucose-6-phosphatase

Type:

PROTEIN

Mol. Mass.:

40569.69

Organism:

Rattus norvegicus

Description:

ChEMBL_835198

Residue:

357

Sequence:

MEERMNVLHDFGIQSTRYLQVNYEDSQDWFVLVSVIADLRNAFYVLFPIWFHIQETVGIN
LLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPLIKQFPVTCETGPGSPSGHA
MGTAGVYYVMVTSTLAIFRGKKKSTYGFRCLNVVLWLGYWAVQLNVCLSRIYLAAHFPHQ
VVAGVLSGIAVAETFSHIRGIYNASLQRYCLITFFLFGFALGFYLLLKGLGVDLLWTLEK
AKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELRKSLPFRLACIV
ASLGLLHLFDSLKPPSQIESIFYILSFCKSATVPFASVSLIPYCLARLLGQTHKKSL

BDBM50294478

n/a

Name

BDBM50294478

Synonyms:

(E)-4-phenyl-1-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)but-3-en-2-one | CHEMBL559970

Type

Small organic molecule

Emp. Form.

C16H20O6

Mol. Mass.

308.3264

SMILES

OC[C@H]1O[C@@H](CC(=O)C=Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O |r,w:8.7|

Structure