| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proto-oncogene Wnt-3 |
|---|
| Ligand | BDBM50294834 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_576549 (CHEMBL1032002) |
|---|
| EC50 | >25000±n/a nM |
|---|
| Citation |  Lu, J; Ma, Z; Hsieh, JC; Fan, CW; Chen, B; Longgood, JC; Williams, NS; Amatruda, JF; Lum, L; Chen, C Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett19:3825-7 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proto-oncogene Wnt-3 |
|---|
| Name: | Proto-oncogene Wnt-3 |
|---|
| Synonyms: | INT4 | Proto-oncogene protein Wnt-3 | WNT3 | WNT3_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39653.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_576549 |
|---|
| Residue: | 355 |
|---|
| Sequence: | MEPHLLGLLLGLLLGGTRVLAGYPIWWSLALGQQYTSLGSQPLLCGSIPGLVPKQLRFCR
NYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIAS
AGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRP
DARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDS
ASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTC
NVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK
|
|
|
|---|
| BDBM50294834 |
|---|
| n/a |
|---|
| Name | BDBM50294834 |
|---|
| Synonyms: | 4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-N-methyl-N-quinolin-8-yl-benzamide | CHEMBL551969 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H21N3O3 |
|---|
| Mol. Mass. | 423.4632 |
|---|
| SMILES | CN(C(=O)c1ccc(cc1)-n1c(O)c2[C@H]3C[C@H](C=C3)c2c1O)c1cccc2cccnc12 |r,c:18| |
|---|
| Structure | 
|
|---|
Search and Browse
