| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interleukin-8 |
|---|
| Ligand | BDBM50169044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_577736 (CHEMBL1052371) |
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| IC50 | 50±n/a nM |
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| Citation |  Sablone, MR; Cesta, MC; Moriconi, A; Aramini, A; Bizzarri, C; Di Giacinto, C; Di Bitondo, R; Gloaguen, I; Aschi, M; Crucianelli, M; Bertini, R; Allegretti, M Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors. Bioorg Med Chem Lett19:4026-30 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Interleukin-8 |
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| Name: | Interleukin-8 |
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| Synonyms: | CXCL8 | IL8 | IL8_HUMAN | MDNCF-a | interleukin 8 precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 11104.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_577736 |
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| Residue: | 99 |
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| Sequence: | MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPH
CANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
|
|
|
|---|
| BDBM50169044 |
|---|
| n/a |
|---|
| Name | BDBM50169044 |
|---|
| Synonyms: | (-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic acid | (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | (R)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid | CHEMBL427526 | IBUPROFEN LYSINE | levibuprofen |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C13H18O2 |
|---|
| Mol. Mass. | 206.2808 |
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| SMILES | CC(C)Cc1ccc(cc1)[C@@H](C)C(O)=O |
|---|
| Structure | 
|
|---|
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