| Reaction Details |
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 | Report a problem with these data |
| Target | NAD kinase |
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| Ligand | BDBM50295366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_578494 (CHEMBL1063153) |
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| IC50 | 280000±n/a nM |
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| Citation |  Petrelli, R; Sham, YY; Chen, L; Felczak, K; Bennett, E; Wilson, D; Aldrich, C; Yu, JS; Cappellacci, L; Franchetti, P; Grifantini, M; Mazzola, F; Di Stefano, M; Magni, G; Pankiewicz, KW Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues. Bioorg Med Chem17:5656-64 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD kinase |
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| Name: | NAD kinase |
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| Synonyms: | NADK | NADK_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49227.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_578494 |
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| Residue: | 446 |
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| Sequence: | MEMEQEKMTMNKELSPDAAAYCCSACHGDETWSYNHPIRGRAKSRSLSASPALGSTKEFR
RTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKMRDASLLQ
PFKELCTHLMEENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDDISNQIDFIIC
LGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRL
KVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVD
VYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVV
PAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFES
LAQCLHWNVRKKQAHFEEEEEEEEEG
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| BDBM50295366 |
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| n/a |
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| Name | BDBM50295366 |
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| Synonyms: | CHEMBL558497 | Di(2'-C-methyladenosine-5'-yl)disulfide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N10O6S2 |
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| Mol. Mass. | 592.651 |
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| SMILES | C[C@@]1(O)[C@H](O)[C@@H](CSSC[C@H]2O[C@@H](n3cnc4c(N)ncnc34)[C@](C)(O)[C@@H]2O)O[C@H]1n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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